CD107a+ (LAMP-1) Cytotoxic CD8+ T-Cells in Lupus Nephritis Patients

Cytotoxic CD8+ T-cells play a pivotal role in the pathogenesis of systemic lupus erythematosus (SLE). The aim of this study was to investigate the role of CD107a (LAMP-1) on cytotoxic CD8+ T-cells in SLE-patients in particular with lupus nephritis. Peripheral blood of SLE-patients (n = 31) and healt...

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Bibliographic Details
Main Authors: Anika Wiechmann, Benjamin Wilde, Bartosz Tyczynski, Kerstin Amann, Wayel H. Abdulahad, Andreas Kribben, Karl Sebastian Lang, Oliver Witzke, Sebastian Dolff
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Medicine
Subjects:
SLE
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.556776/full