Immune Exhaustion: Past Lessons and New Insights from Lymphocytic Choriomeningitis Virus

Lymphocytic choriomeningitis virus (LCMV) is a paradigm-forming experimental system with a remarkable track record of contributing to the discovery of many of the fundamental concepts of modern immunology. The ability of LCMV to establish a chronic infection in immunocompetent adult mice was instrum...

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Bibliographic Details
Main Authors: Shannon M. Kahan, Allan J. Zajac
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/2/156