Management of brain metastasis in a patient with advanced epithelial ovarian carcinoma by gamma-knife radiosurgery
Introduction. Brain metastases from epithelial ovarian cancer (EOC) are rare events. We present a rare case of single ovarian cancer metastasis to the brain treated with gamma-knife radiosurgery (GKRS). Case Outline. A 65-year-old woman with advanced EOC presented with severe neurologic...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Serbian Medical Society
2015-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2015/0370-81791504205N.pdf |
| Summary: | Introduction. Brain metastases from epithelial ovarian cancer (EOC) are rare
events. We present a rare case of single ovarian cancer metastasis to the
brain treated with gamma-knife radiosurgery (GKRS). Case Outline. A
65-year-old woman with advanced EOC presented with severe neurologic
symptoms. A single brain metastasis of 3.2 cm with surrounding edema in the
left parietal lobe was detected by brain magnetic resonance imaging (MRI)
scan during the work-up. The decision to perform GKRS was due to a surgical
inaccessibility of intracranial lesion. Twelve weeks after the procedure, the
MRI scan showed reduction in the diameter of brain metastasis and surrounding
edema and the patient returned to good mental and motor performance. The
patient survived for 22 months following treatment and died from a
progressive intra-abdominal disease. Prognosis of ovarian cancer patients
with brain metastases is generally poor regardless of treatment. Conclusion.
Our case shows that GKRS as primary treatment modality for the control of
ovarian cancer metastases to the brain was effective and can be considered as
a treatment of choice if international selection criteria are followed. |
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| ISSN: | 0370-8179 |