A Comprehensive View of the Structural and Functional Alterations of Extracellular Matrix by Snake Venom Metalloproteinases (SVMPs): Novel Perspectives on the Pathophysiology of Envenoming

A Comprehensive View of the Structural and Functional Alterations of Extracellular Matrix by Snake Venom Metalloproteinases (SVMPs): Novel Perspectives on the Pathophysiology of Envenoming

Snake venom metalloproteinases (SVMPs) affect the extracellular matrix (ECM) in multiple and complex ways. Previously, the combination of various methodological platforms, including electron microscopy, histochemistry, immunohistochemistry, and Western blot, has allowed a partial understanding of su...

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Bibliographic Details
Main Authors: José María Gutiérrez, Teresa Escalante, Alexandra Rucavado, Cristina Herrera, Jay W. Fox
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Toxins
Subjects:
proteomics
exudate
extracellular matrix
basement membrane
hemorrhage
snake venom metalloproteinases
FACITs
Online Access:http://www.mdpi.com/2072-6651/8/10/304

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