Cutaneous vasculitis and granulomatous hepatitis as paradoxical adverse events of Infliximab

Biological agents revolutionised the treatment of inflammatory arthropathies. Paradoxical adverse events (PAEs) are rare immunological side effects caused by such agents. The authors report concurrent presentation of two rare PAEs of tumor-necrosis-factor alpha inhibitors (iTNFa) – cutaneous vasculi...

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Main Authors:	DIogo Esperança Almeida, Emanuel Costa, Joana Sousa Neves, Marcos Cerqueira, Ana Roxo Ribeiro
Format:	Article
Language:	English
Published:	Sociedade Portuguesa de Reumatologia 2020-04-01
Series:	Acta Reumatológica Portuguesa
Subjects:	psoriatic arthritis paradoxical adverse events anti-tnf drugs
Online Access:	http://www.actareumatologica.pt/files/article/1309_cutaneous_vasculitis_and_granulomatous_hepatitis_as_paradoxical_adverse_events_of_infliximab_file.pdf

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spelling	doaj-db8310b576fb4e5ba00f1e75bc8f9c4b2020-11-25T03:56:55ZengSociedade Portuguesa de ReumatologiaActa Reumatológica Portuguesa0303-464X2020-04-0120202156157CE200063Cutaneous vasculitis and granulomatous hepatitis as paradoxical adverse events of InfliximabDIogo Esperança Almeida0Emanuel Costa1Joana Sousa Neves2Marcos Cerqueira3Ana Roxo Ribeiro4Hospital de BragaHospital de BragaHospital de BragaHospital de BragaHospital de BragaBiological agents revolutionised the treatment of inflammatory arthropathies. Paradoxical adverse events (PAEs) are rare immunological side effects caused by such agents. The authors report concurrent presentation of two rare PAEs of tumor-necrosis-factor alpha inhibitors (iTNFa) – cutaneous vasculitis and granulomatous hepatitis – in a patient with psoriatic arthritis treated with infliximab and briefly discuss aspects of diagnosis, pathophysiology and management of such events in light of the available evidence.http://www.actareumatologica.pt/files/article/1309_cutaneous_vasculitis_and_granulomatous_hepatitis_as_paradoxical_adverse_events_of_infliximab_file.pdfpsoriatic arthritisparadoxical adverse eventsanti-tnf drugs
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	DIogo Esperança Almeida Emanuel Costa Joana Sousa Neves Marcos Cerqueira Ana Roxo Ribeiro
spellingShingle	DIogo Esperança Almeida Emanuel Costa Joana Sousa Neves Marcos Cerqueira Ana Roxo Ribeiro Cutaneous vasculitis and granulomatous hepatitis as paradoxical adverse events of Infliximab Acta Reumatológica Portuguesa psoriatic arthritis paradoxical adverse events anti-tnf drugs
author_facet	DIogo Esperança Almeida Emanuel Costa Joana Sousa Neves Marcos Cerqueira Ana Roxo Ribeiro
author_sort	DIogo Esperança Almeida
title	Cutaneous vasculitis and granulomatous hepatitis as paradoxical adverse events of Infliximab
title_short	Cutaneous vasculitis and granulomatous hepatitis as paradoxical adverse events of Infliximab
title_full	Cutaneous vasculitis and granulomatous hepatitis as paradoxical adverse events of Infliximab
title_fullStr	Cutaneous vasculitis and granulomatous hepatitis as paradoxical adverse events of Infliximab
title_full_unstemmed	Cutaneous vasculitis and granulomatous hepatitis as paradoxical adverse events of Infliximab
title_sort	cutaneous vasculitis and granulomatous hepatitis as paradoxical adverse events of infliximab
publisher	Sociedade Portuguesa de Reumatologia
series	Acta Reumatológica Portuguesa
issn	0303-464X
publishDate	2020-04-01
description	Biological agents revolutionised the treatment of inflammatory arthropathies. Paradoxical adverse events (PAEs) are rare immunological side effects caused by such agents. The authors report concurrent presentation of two rare PAEs of tumor-necrosis-factor alpha inhibitors (iTNFa) – cutaneous vasculitis and granulomatous hepatitis – in a patient with psoriatic arthritis treated with infliximab and briefly discuss aspects of diagnosis, pathophysiology and management of such events in light of the available evidence.
topic	psoriatic arthritis paradoxical adverse events anti-tnf drugs
url	http://www.actareumatologica.pt/files/article/1309_cutaneous_vasculitis_and_granulomatous_hepatitis_as_paradoxical_adverse_events_of_infliximab_file.pdf
work_keys_str_mv	AT diogoesperancaalmeida cutaneousvasculitisandgranulomatoushepatitisasparadoxicaladverseeventsofinfliximab AT emanuelcosta cutaneousvasculitisandgranulomatoushepatitisasparadoxicaladverseeventsofinfliximab AT joanasousaneves cutaneousvasculitisandgranulomatoushepatitisasparadoxicaladverseeventsofinfliximab AT marcoscerqueira cutaneousvasculitisandgranulomatoushepatitisasparadoxicaladverseeventsofinfliximab AT anaroxoribeiro cutaneousvasculitisandgranulomatoushepatitisasparadoxicaladverseeventsofinfliximab
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Cutaneous vasculitis and granulomatous hepatitis as paradoxical adverse events of Infliximab

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