In Silico-Based Design and In Vivo Evaluation of an Anthranilic Acid Derivative as a Multitarget Drug in a Diet-Induced Metabolic Syndrome Model

In Silico-Based Design and In Vivo Evaluation of an Anthranilic Acid Derivative as a Multitarget Drug in a Diet-Induced Metabolic Syndrome Model

Metabolic syndrome (MetS) is a complex disease that affects almost a quarter of the world’s adult population. In MetS, diabetes, obesity, hyperglycemia, high cholesterol, and high blood pressure are the most common disorders. Polypharmacy is the most used strategy for managing conditions related to...

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Bibliographic Details
Main Authors: Héctor González-Álvarez, Astrid Bravo-Jiménez, Matilda Martínez-Arellanes, Gabriela Odette Gamboa-Osorio, Edwin Chávez-Gutiérrez, Lino A. González-Hernández, Karina Gallardo-Ignacio, Osvaldo J. Quintana-Romero, Armando Ariza-Castolo, Christian Guerra-Araiza, Laura Martino-Roaro, Dulce María Meneses-Ruiz, Rodolfo Pinto-Almazán, Marco A. Loza-Mejía
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceuticals
Subjects:
metabolic syndrome
multitarget drug
molecular docking
in vivo evaluation
toxicity
Online Access:https://www.mdpi.com/1424-8247/14/9/914

Internet

https://www.mdpi.com/1424-8247/14/9/914

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