Chromosome-biased binding and gene regulation by the Caenorhabditis elegans DRM complex.

Chromosome-biased binding and gene regulation by the Caenorhabditis elegans DRM complex.

DRM is a conserved transcription factor complex that includes E2F/DP and pRB family proteins and plays important roles in development and cancer. Here we describe new aspects of DRM binding and function revealed through genome-wide analyses of the Caenorhabditis elegans DRM subunit LIN-54. We show t...

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Bibliographic Details
Main Authors: Tomoko M Tabuchi, Bart Deplancke, Naoki Osato, Lihua J Zhu, M Inmaculada Barrasa, Melissa M Harrison, H Robert Horvitz, Albertha J M Walhout, Kirsten A Hagstrom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3093354?pdf=render

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