Identification of Pathway-Specific Protein Domain by Incorporating Hyperparameter Optimization Based on 2D Convolutional Neural Network

Identification of Pathway-Specific Protein Domain by Incorporating Hyperparameter Optimization Based on 2D Convolutional Neural Network

Pathway-specific protein domain (PSPD) are associated with specific pathways. Many protein domains are pervasive in various biological processes, whereas other domains are linked to specific pathways. Many human disease pathways, such as cancer pathways and signaling pathway-related diseases, have c...

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Bibliographic Details
Main Authors: Ali Ghualm, Xiujuan Lei, Yuchen Zhang, Shi Cheng, Min Guo
Format: Article
Language:English
Published: IEEE 2020-01-01
Series:IEEE Access
Subjects:
Molecular structure prediction
deep learning
convolutional neural network
evolutionary knowledge
multiple features
Online Access:https://ieeexplore.ieee.org/document/9210038/

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