The Cell Cycle Inhibitors p21Cip1 and p27Kip1 Control Proliferation but Enhance DNA Damage Resistance of Glioma Stem Cells

The Cell Cycle Inhibitors p21Cip1 and p27Kip1 Control Proliferation but Enhance DNA Damage Resistance of Glioma Stem Cells

High-grade gliomas are the most prevalent and lethal primary brain tumors. They display a hierarchical arrangement with a population of self-renewing and highly tumorigenic cells called cancer stem cells. These cells are thought to be responsible for tumor recurrence, which make them main candidates...

Full description

Bibliographic Details
Main Authors: Olivia Morris-Hanon, Verónica Alejandra Furmento, María Soledad Rodríguez-Varela, Sofía Mucci, Damián Darío Fernandez-Espinosa, Leonardo Romorini, Gustavo Emilio Sevlever, María Elida Scassa, Guillermo Agustín Videla-Richardson
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558617300441

Internet

http://www.sciencedirect.com/science/article/pii/S1476558617300441

Similar Items