8-Chloro-cAMP-Related Changes on Mice Uteri

8-Chloro-cAMP-Related Changes on Mice Uteri

Histopathological effects of cAMP analog (8-Chloro-cAMP), tamoxifen, and medroxyprogesterone, alone or combined, upon BALB/c mice uteri are reported. 8-Chloro-cAMP diminished uterine weight, but did not modify its histopathology or estral cycle significantly. Tamoxifen diminished uterine weight show...

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Main Authors: Andrea Actis, Maximo Croci, Emanuel Levin, Rosa Bergoc
Format: Article
Language:English
Published: Hindawi Limited 2002-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2002.282
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spelling doaj-db23725ff0534a12a0cb24e7fc63cc4a2020-11-25T01:40:37ZengHindawi LimitedThe Scientific World Journal1537-744X2002-01-0121426143210.1100/tsw.2002.2828-Chloro-cAMP-Related Changes on Mice UteriAndrea Actis0Maximo Croci1Emanuel Levin2Rosa Bergoc3Department of Human Biochemistry, School of Medicine, University of Buenos Aires, Buenos Aires, ArgentinaInstitute of Immunooncology Dr. J.V. Crescenti, Buenos Aires, ArgentinaDepartment of Human Biochemistry, School of Medicine, University of Buenos Aires, Buenos Aires, ArgentinaRadioisotopes Laboratory, School of Pharmacy and Biochemistry, University of Buenos Aires, Junin St. 956 (1113), Buenos Aires, ArgentinaHistopathological effects of cAMP analog (8-Chloro-cAMP), tamoxifen, and medroxyprogesterone, alone or combined, upon BALB/c mice uteri are reported. 8-Chloro-cAMP diminished uterine weight, but did not modify its histopathology or estral cycle significantly. Tamoxifen diminished uterine weight showing cystic hyperplasia and an estral cycle arrested at diestrus. Medroxyprogesterone increased uterine weight, caused a swelling of the endometrium and a pseudopregnancy estrus. When combined with 8-Chloro-cAMP, tamoxifen or medroxyprogesterone always had a predominant effect. We concluded that the effects of 8-Chloro-cAMP on mice uteri did not cause significant changes on its histopathology, but diminished its weight.http://dx.doi.org/10.1100/tsw.2002.282
collection DOAJ
language English
format Article
sources DOAJ
author Andrea Actis
Maximo Croci
Emanuel Levin
Rosa Bergoc
spellingShingle Andrea Actis
Maximo Croci
Emanuel Levin
Rosa Bergoc
8-Chloro-cAMP-Related Changes on Mice Uteri
The Scientific World Journal
author_facet Andrea Actis
Maximo Croci
Emanuel Levin
Rosa Bergoc
author_sort Andrea Actis
title 8-Chloro-cAMP-Related Changes on Mice Uteri
title_short 8-Chloro-cAMP-Related Changes on Mice Uteri
title_full 8-Chloro-cAMP-Related Changes on Mice Uteri
title_fullStr 8-Chloro-cAMP-Related Changes on Mice Uteri
title_full_unstemmed 8-Chloro-cAMP-Related Changes on Mice Uteri
title_sort 8-chloro-camp-related changes on mice uteri
publisher Hindawi Limited
series The Scientific World Journal
issn 1537-744X
publishDate 2002-01-01
description Histopathological effects of cAMP analog (8-Chloro-cAMP), tamoxifen, and medroxyprogesterone, alone or combined, upon BALB/c mice uteri are reported. 8-Chloro-cAMP diminished uterine weight, but did not modify its histopathology or estral cycle significantly. Tamoxifen diminished uterine weight showing cystic hyperplasia and an estral cycle arrested at diestrus. Medroxyprogesterone increased uterine weight, caused a swelling of the endometrium and a pseudopregnancy estrus. When combined with 8-Chloro-cAMP, tamoxifen or medroxyprogesterone always had a predominant effect. We concluded that the effects of 8-Chloro-cAMP on mice uteri did not cause significant changes on its histopathology, but diminished its weight.
url http://dx.doi.org/10.1100/tsw.2002.282
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AT maximocroci 8chlorocamprelatedchangesonmiceuteri
AT emanuellevin 8chlorocamprelatedchangesonmiceuteri
AT rosabergoc 8chlorocamprelatedchangesonmiceuteri
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