Postoperative endophthalmitis due to multidrug-resistant Klebsiella pneumoniae treated successfully with intravitreal colistin and core vitrectomy

Postoperative endophthalmitis due to multidrug-resistant Klebsiella pneumoniae treated successfully with intravitreal colistin and core vitrectomy

We report a case of Klebsiella-related multidrug-resistant (MDR) postoperative endophthalmitis in a 60-year-old male treated successfully with colistin and core vitrectomy. Vision in the affected left eye (LE) at presentation was hand movements. Vitreous tap with intravitreal antibiotics (vancomyci...

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Bibliographic Details
Main Authors: Amit Kumar Deb, Sujatha Sistla, Sushmita Sana Chowdhury, Ajax Jossy, Nirupama Kasturi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Kerala Journal of Ophthalmology
Subjects:
intravitreal colistin
klebsiella pneumoniae
multidrug-resistant endophthalmitis
Online Access:http://www.kjophthal.com/article.asp?issn=0976-6677;year=2020;volume=32;issue=2;spage=183;epage=185;aulast=Deb
Description
Summary:We report a case of Klebsiella-related multidrug-resistant (MDR) postoperative endophthalmitis in a 60-year-old male treated successfully with colistin and core vitrectomy. Vision in the affected left eye (LE) at presentation was hand movements. Vitreous tap with intravitreal antibiotics (vancomycin and ceftazidime) showed no clinical improvement after 48 h. Gram stain of vitreous sample showed Gram-negative bacilli. Bacterial culture showed MDR Klebsiella pneumoniae isolates with sensitivity only to colistin. LE core vitrectomy was performed and intravitreal colistin was administered. At 1 month, vision in LE improved to 20/20 with no subsequent recurrence.
ISSN:0976-6677

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