Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2−/− mice[S]

Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2−/− mice[S]

Bile acid imbalance causes progressive familial intrahepatic cholestasis type 2 (PFIC2) or type 3 (PFIC3), severe liver diseases associated with genetic defects in the biliary bile acid transporter bile salt export pump (BSEP; ABCB11) or phosphatidylcholine transporter multidrug resistance protein 3...

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Bibliographic Details
Main Authors: Renxue Wang, Jonathan A. Sheps, Lin Liu, Jun Han, Patrick S.K. Chen, Jason Lamontagne, Peter D. Wilson, Ian Welch, Christoph H. Borchers, Victor Ling
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Lipid Research
Subjects:
bile acids and salts/biosynthesis
cancer
gene expression
hepatic cellular carcinoma
hydrophobicity
inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520326675

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