Opportunities and challenges for junior investigators conducting pain clinical trials

Abstract. Introduction:. Clinical investigation serves a vital role to advance treatment and management strategies for patients with pain. For those new to clinical investigation, key advice for both the novice clinical investigator and the experienced researcher expanding to translational work may...

Full description

Bibliographic Details
Main Authors: Meredith C.B. Adams, Mark C. Bicket, Jamie D. Murphy, Christopher L. Wu, Robert W. Hurley
Format: Article
Language:English
Published: Wolters Kluwer 2019-06-01
Series:PAIN Reports
Online Access:http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000639
id doaj-db1736e94852489582bd8ad8fb1d348a
record_format Article
spelling doaj-db1736e94852489582bd8ad8fb1d348a2020-11-25T02:37:34ZengWolters KluwerPAIN Reports2471-25312019-06-0143e63910.1097/PR9.0000000000000639201906000-00030Opportunities and challenges for junior investigators conducting pain clinical trialsMeredith C.B. Adams0Mark C. Bicket1Jamie D. Murphy2Christopher L. Wu3Robert W. Hurley4a Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USAb Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins School of Medicine, Baltimore, MD, USAb Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins School of Medicine, Baltimore, MD, USAb Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins School of Medicine, Baltimore, MD, USAa Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USAAbstract. Introduction:. Clinical investigation serves a vital role to advance treatment and management strategies for patients with pain. For those new to clinical investigation, key advice for both the novice clinical investigator and the experienced researcher expanding to translational work may accelerate research efforts. Objective:. To review foundational material relevant to junior investigators focusing on pain clinical trials, with an emphasis on randomized controlled trials. Methods:. We reviewed recent publications and resources relevant to clinical investigators, with a particular emphasis on pain research. Results:. Understanding the approaches and barriers to clinical pain research is a first step to building a successful investigative portfolio. Key components of professional development include motivation, mentorship, and collaborative approaches to research. Many junior clinical investigators face challenges in pursing research careers and sparking iterative progress toward success in clinical trials. Pain-specific research metrics and goals—including hypothesis development, study design considerations, and regulatory concerns—are also important considerations to junior investigators who pursue clinical trails. Approaches to build toward collaborative and independent funding are essential for investigators. Conclusion:. This work provides a foundation for understanding the clinical research process and helps inform the goals and plans of clinical investigators.http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000639
collection DOAJ
language English
format Article
sources DOAJ
author Meredith C.B. Adams
Mark C. Bicket
Jamie D. Murphy
Christopher L. Wu
Robert W. Hurley
spellingShingle Meredith C.B. Adams
Mark C. Bicket
Jamie D. Murphy
Christopher L. Wu
Robert W. Hurley
Opportunities and challenges for junior investigators conducting pain clinical trials
PAIN Reports
author_facet Meredith C.B. Adams
Mark C. Bicket
Jamie D. Murphy
Christopher L. Wu
Robert W. Hurley
author_sort Meredith C.B. Adams
title Opportunities and challenges for junior investigators conducting pain clinical trials
title_short Opportunities and challenges for junior investigators conducting pain clinical trials
title_full Opportunities and challenges for junior investigators conducting pain clinical trials
title_fullStr Opportunities and challenges for junior investigators conducting pain clinical trials
title_full_unstemmed Opportunities and challenges for junior investigators conducting pain clinical trials
title_sort opportunities and challenges for junior investigators conducting pain clinical trials
publisher Wolters Kluwer
series PAIN Reports
issn 2471-2531
publishDate 2019-06-01
description Abstract. Introduction:. Clinical investigation serves a vital role to advance treatment and management strategies for patients with pain. For those new to clinical investigation, key advice for both the novice clinical investigator and the experienced researcher expanding to translational work may accelerate research efforts. Objective:. To review foundational material relevant to junior investigators focusing on pain clinical trials, with an emphasis on randomized controlled trials. Methods:. We reviewed recent publications and resources relevant to clinical investigators, with a particular emphasis on pain research. Results:. Understanding the approaches and barriers to clinical pain research is a first step to building a successful investigative portfolio. Key components of professional development include motivation, mentorship, and collaborative approaches to research. Many junior clinical investigators face challenges in pursing research careers and sparking iterative progress toward success in clinical trials. Pain-specific research metrics and goals—including hypothesis development, study design considerations, and regulatory concerns—are also important considerations to junior investigators who pursue clinical trails. Approaches to build toward collaborative and independent funding are essential for investigators. Conclusion:. This work provides a foundation for understanding the clinical research process and helps inform the goals and plans of clinical investigators.
url http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000639
work_keys_str_mv AT meredithcbadams opportunitiesandchallengesforjuniorinvestigatorsconductingpainclinicaltrials
AT markcbicket opportunitiesandchallengesforjuniorinvestigatorsconductingpainclinicaltrials
AT jamiedmurphy opportunitiesandchallengesforjuniorinvestigatorsconductingpainclinicaltrials
AT christopherlwu opportunitiesandchallengesforjuniorinvestigatorsconductingpainclinicaltrials
AT robertwhurley opportunitiesandchallengesforjuniorinvestigatorsconductingpainclinicaltrials
_version_ 1724794663798308864