Glyceollin I Reverses Epithelial to Mesenchymal Transition in Letrozole Resistant Breast Cancer through ZEB1

Glyceollin I Reverses Epithelial to Mesenchymal Transition in Letrozole Resistant Breast Cancer through ZEB1

Although aromatase inhibitors are standard endocrine therapy for postmenopausal women with early-stage metastatic estrogen-dependent breast cancer, they are limited by the development of drug resistance. A better understanding of this process is critical towards designing novel strategies for diseas...

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Bibliographic Details
Main Authors: Patrick P. Carriere, Shawn D. Llopis, Anna C. Naiki, Gina Nguyen, Tina Phan, Mary M. Nguyen, Lynez C. Preyan, Letitia Yearby, Jamal Pratt, Hope Burks, Ian R. Davenport, Thu A. Nguyen, KiTani Parker-Lemieux, Florastina Payton-Stewart, Christopher C. Williams, Stephen M. Boué, Matthew E. Burow, Bridgette Collins-Burow, Aaron Hilliard, A. Michael Davidson, Syreeta L. Tilghman
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Environmental Research and Public Health
Subjects:
letrozole resistance
epithelial mesenchymal transition
breast cancer
phytochemicals
aromatase inhibitors
metastasis
Online Access:http://www.mdpi.com/1660-4601/13/1/10

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