1,5-Phosphonium betaines from N-triflylpropiolamides, triphenylphosphane, and active methylene compounds

1,5-Phosphonium betaines from N-triflylpropiolamides, triphenylphosphane, and active methylene compounds

N-Phenyl-N-(trifluoromethylsulfonyl)propiolamides react with triphenylphosphane in the presence of various active methylene compounds CH2XY in a 1:1:1 molar ratio to furnish 1-phosphonium-5-oxabetaines, Ph3P+–C(R)=CH–C(O–)=CXY. These betaines are formed preferentially, but not exclusively, as E-dias...

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Bibliographic Details
Main Authors: Vito A. Fiore, Chiara Freisler, Gerhard Maas
Format: Article
Language:English
Published: Beilstein-Institut 2019-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
betaines
multi-component reactions
n-triflylamides
phospha-michael reaction
propiolamides
Online Access:https://doi.org/10.3762/bjoc.15.253

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