Injectable Glycol Chitosan Hydrogel Containing Folic Acid-Functionalized Cyclodextrin-Paclitaxel Complex for Breast Cancer Therapy

Injectable Glycol Chitosan Hydrogel Containing Folic Acid-Functionalized Cyclodextrin-Paclitaxel Complex for Breast Cancer Therapy

We prepared a drug carrier which consisted of injectable methacrylated glycol chitosan (MGC) hydrogel, and a conjugate of 6-monodeoxy-6-monoamino-β-cyclodextrin⋅hydrochloride (6-NH<sub>2</sub>-β-CD⋅HCl), polyethylene glycol (PEG), and folic acid (FA) for the local delivery and improved c...

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Bibliographic Details
Main Authors: Hoon Hyun, Min Ho Park, Gayoung Jo, Bo Young Lee, Jae Won Choi, Heung Jae Chun, Hyeon Soo Kim, Dae Hyeok Yang
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Nanomaterials
Subjects:
glycol chitosan
beta-cyclodextrin
polyethylene glycol
folic acid
breast cancer therapy
Online Access:https://www.mdpi.com/2079-4991/11/2/317

Internet

https://www.mdpi.com/2079-4991/11/2/317

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