Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection
Objective. To evaluate the recurrence rate of bulbar urethral strictures managed with cold knife direct vision internal urethrotomy and high dose corticosteroid injection. Methods. 28 patients with bulbar urethral strictures underwent direct vision internal urethrotomy with high dose triamcinolone i...
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2015-01-01
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Series: | Advances in Urology |
Online Access: | http://dx.doi.org/10.1155/2015/281969 |
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doaj-daf5403bd0eb476b8ac959ae8f34646a2020-11-24T23:15:37ZengHindawi LimitedAdvances in Urology1687-63691687-63772015-01-01201510.1155/2015/281969281969Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone InjectionRishi Modh0Peter Y. Cai1Alyssa Sheffield2Lawrence L. Yeung3Department of Urology, University of Florida College of Medicine, Gainesville, FL 32608, USADepartment of Urology, University of Florida College of Medicine, Gainesville, FL 32608, USADepartment of Urology, University of Florida College of Medicine, Gainesville, FL 32608, USADepartment of Urology, University of Florida College of Medicine, Gainesville, FL 32608, USAObjective. To evaluate the recurrence rate of bulbar urethral strictures managed with cold knife direct vision internal urethrotomy and high dose corticosteroid injection. Methods. 28 patients with bulbar urethral strictures underwent direct vision internal urethrotomy with high dose triamcinolone injection into the periurethral tissue and were followed up for recurrence. Results. Our cohort had a mean age of 60 years and average stricture length of 1.85 cm, and 71% underwent multiple previous urethral stricture procedures with an average of 5.7 procedures each. Our technique modification of high dose corticosteroid injection had a recurrence rate of 29% at a mean follow-up of 20 months with a low rate of urinary tract infections. In patients who failed treatment, mean time to stricture recurrence was 7 months. Patients who were successfully treated had significantly better International Prostate Symptom Scores at 6, 9, and 12 months. There was no significant difference in maximum flow velocity on Uroflowmetry at last follow-up but there was significant difference in length of follow-up (p=0.02). Conclusions. High dose corticosteroid injection at the time of direct vision internal urethrotomy is a safe and effective procedure to delay anatomical and symptomatic recurrence of bulbar urethral strictures, particularly in those who are poor candidates for urethroplasty.http://dx.doi.org/10.1155/2015/281969 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rishi Modh Peter Y. Cai Alyssa Sheffield Lawrence L. Yeung |
spellingShingle |
Rishi Modh Peter Y. Cai Alyssa Sheffield Lawrence L. Yeung Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection Advances in Urology |
author_facet |
Rishi Modh Peter Y. Cai Alyssa Sheffield Lawrence L. Yeung |
author_sort |
Rishi Modh |
title |
Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection |
title_short |
Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection |
title_full |
Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection |
title_fullStr |
Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection |
title_full_unstemmed |
Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection |
title_sort |
outcomes of direct vision internal urethrotomy for bulbar urethral strictures: technique modification with high dose triamcinolone injection |
publisher |
Hindawi Limited |
series |
Advances in Urology |
issn |
1687-6369 1687-6377 |
publishDate |
2015-01-01 |
description |
Objective. To evaluate the recurrence rate of bulbar urethral strictures managed with cold knife direct vision internal urethrotomy and high dose corticosteroid injection. Methods. 28 patients with bulbar urethral strictures underwent direct vision internal urethrotomy with high dose triamcinolone injection into the periurethral tissue and were followed up for recurrence. Results. Our cohort had a mean age of 60 years and average stricture length of 1.85 cm, and 71% underwent multiple previous urethral stricture procedures with an average of 5.7 procedures each. Our technique modification of high dose corticosteroid injection had a recurrence rate of 29% at a mean follow-up of 20 months with a low rate of urinary tract infections. In patients who failed treatment, mean time to stricture recurrence was 7 months. Patients who were successfully treated had significantly better International Prostate Symptom Scores at 6, 9, and 12 months. There was no significant difference in maximum flow velocity on Uroflowmetry at last follow-up but there was significant difference in length of follow-up (p=0.02). Conclusions. High dose corticosteroid injection at the time of direct vision internal urethrotomy is a safe and effective procedure to delay anatomical and symptomatic recurrence of bulbar urethral strictures, particularly in those who are poor candidates for urethroplasty. |
url |
http://dx.doi.org/10.1155/2015/281969 |
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