Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection

Objective. To evaluate the recurrence rate of bulbar urethral strictures managed with cold knife direct vision internal urethrotomy and high dose corticosteroid injection. Methods. 28 patients with bulbar urethral strictures underwent direct vision internal urethrotomy with high dose triamcinolone i...

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Main Authors: Rishi Modh, Peter Y. Cai, Alyssa Sheffield, Lawrence L. Yeung
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2015/281969
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spelling doaj-daf5403bd0eb476b8ac959ae8f34646a2020-11-24T23:15:37ZengHindawi LimitedAdvances in Urology1687-63691687-63772015-01-01201510.1155/2015/281969281969Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone InjectionRishi Modh0Peter Y. Cai1Alyssa Sheffield2Lawrence L. Yeung3Department of Urology, University of Florida College of Medicine, Gainesville, FL 32608, USADepartment of Urology, University of Florida College of Medicine, Gainesville, FL 32608, USADepartment of Urology, University of Florida College of Medicine, Gainesville, FL 32608, USADepartment of Urology, University of Florida College of Medicine, Gainesville, FL 32608, USAObjective. To evaluate the recurrence rate of bulbar urethral strictures managed with cold knife direct vision internal urethrotomy and high dose corticosteroid injection. Methods. 28 patients with bulbar urethral strictures underwent direct vision internal urethrotomy with high dose triamcinolone injection into the periurethral tissue and were followed up for recurrence. Results. Our cohort had a mean age of 60 years and average stricture length of 1.85 cm, and 71% underwent multiple previous urethral stricture procedures with an average of 5.7 procedures each. Our technique modification of high dose corticosteroid injection had a recurrence rate of 29% at a mean follow-up of 20 months with a low rate of urinary tract infections. In patients who failed treatment, mean time to stricture recurrence was 7 months. Patients who were successfully treated had significantly better International Prostate Symptom Scores at 6, 9, and 12 months. There was no significant difference in maximum flow velocity on Uroflowmetry at last follow-up but there was significant difference in length of follow-up (p=0.02). Conclusions. High dose corticosteroid injection at the time of direct vision internal urethrotomy is a safe and effective procedure to delay anatomical and symptomatic recurrence of bulbar urethral strictures, particularly in those who are poor candidates for urethroplasty.http://dx.doi.org/10.1155/2015/281969
collection DOAJ
language English
format Article
sources DOAJ
author Rishi Modh
Peter Y. Cai
Alyssa Sheffield
Lawrence L. Yeung
spellingShingle Rishi Modh
Peter Y. Cai
Alyssa Sheffield
Lawrence L. Yeung
Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection
Advances in Urology
author_facet Rishi Modh
Peter Y. Cai
Alyssa Sheffield
Lawrence L. Yeung
author_sort Rishi Modh
title Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection
title_short Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection
title_full Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection
title_fullStr Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection
title_full_unstemmed Outcomes of Direct Vision Internal Urethrotomy for Bulbar Urethral Strictures: Technique Modification with High Dose Triamcinolone Injection
title_sort outcomes of direct vision internal urethrotomy for bulbar urethral strictures: technique modification with high dose triamcinolone injection
publisher Hindawi Limited
series Advances in Urology
issn 1687-6369
1687-6377
publishDate 2015-01-01
description Objective. To evaluate the recurrence rate of bulbar urethral strictures managed with cold knife direct vision internal urethrotomy and high dose corticosteroid injection. Methods. 28 patients with bulbar urethral strictures underwent direct vision internal urethrotomy with high dose triamcinolone injection into the periurethral tissue and were followed up for recurrence. Results. Our cohort had a mean age of 60 years and average stricture length of 1.85 cm, and 71% underwent multiple previous urethral stricture procedures with an average of 5.7 procedures each. Our technique modification of high dose corticosteroid injection had a recurrence rate of 29% at a mean follow-up of 20 months with a low rate of urinary tract infections. In patients who failed treatment, mean time to stricture recurrence was 7 months. Patients who were successfully treated had significantly better International Prostate Symptom Scores at 6, 9, and 12 months. There was no significant difference in maximum flow velocity on Uroflowmetry at last follow-up but there was significant difference in length of follow-up (p=0.02). Conclusions. High dose corticosteroid injection at the time of direct vision internal urethrotomy is a safe and effective procedure to delay anatomical and symptomatic recurrence of bulbar urethral strictures, particularly in those who are poor candidates for urethroplasty.
url http://dx.doi.org/10.1155/2015/281969
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