HIV-1 buds predominantly at the plasma membrane of primary human macrophages.
HIV-1 assembly and release are believed to occur at the plasma membrane in most host cells with the exception of primary macrophages, for which exclusive budding at late endosomes has been reported. Here, we applied a novel ultrastructural approach to assess HIV-1 budding in primary macrophages in a...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-03-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC1829407?pdf=render |