Systematic analysis of the effects of different nitrogen source and ICDH knockout on glycolate synthesis in Escherichia coli

Systematic analysis of the effects of different nitrogen source and ICDH knockout on glycolate synthesis in Escherichia coli

Abstract Background Glycolate is an important α-hydroxy carboxylic acid widely used in industrial and consumer applications. The production of glycolate from glucose in Escherichia coli is generally carried out by glycolysis and glyoxylate shunt pathways, followed by reduction to glycolate. Glycolat...

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Bibliographic Details
Main Authors: Kangjia Zhu, Guohui Li, Ren Wei, Yin Mao, Yunying Zhao, Aiyong He, Zhonghu Bai, Yu Deng
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Biological Engineering
Subjects:
Escherichia coli
Glycolate
RNA-Seq
Organic nitrogen source
ICDH knockout
Online Access:http://link.springer.com/article/10.1186/s13036-019-0159-2

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