Fatty acid-binding protein 4 impairs the insulin-dependent nitric oxide pathway in vascular endothelial cells

Fatty acid-binding protein 4 impairs the insulin-dependent nitric oxide pathway in vascular endothelial cells

<p>Abstract</p> <p>Background</p> <p>Recent studies have shown that fatty acid-binding protein 4 (FABP4) plasma levels are associated with impaired endothelial function in type 2 diabetes (T2D). In this work, we analysed the effect of FABP4 on the insulin-mediated nitri...

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Bibliographic Details
Main Authors: Aragonès Gemma, Saavedra Paula, Heras Mercedes, Cabré Anna, Girona Josefa, Masana Lluís
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Cardiovascular Diabetology
Subjects:
Diabetes
Endothelium
Fatty acid-binding protein 4 (FABP4)
Endothelial dysfunction
Insulin
Insulin-signalling pathway
Endothelial nitric oxide synthase (eNOS)
Nitric oxide (NO)
Online Access:http://www.cardiab.com/content/11/1/72

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