Switching on Endogenous Metal Binding Proteins in Parkinson’s Disease

Switching on Endogenous Metal Binding Proteins in Parkinson’s Disease

The formation of cytotoxic intracellular protein aggregates is a pathological signature of multiple neurodegenerative diseases. The principle aggregating protein in Parkinson’s disease (PD) and atypical Parkinson’s diseases is α-synuclein (α-syn), which occurs i...

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Bibliographic Details
Main Authors: Fleur A. McLeary, Alexandre N. Rcom-H’cheo-Gauthier, Michael Goulding, Rowan A. W. Radford, Yuho Okita, Peter Faller, Roger S. Chung, Dean L. Pountney
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cells
Subjects:
copper
iron
calcium
alpha-synuclein
Parkinson’s disease
metallothionein
calbindin
ferritin
Online Access:https://www.mdpi.com/2073-4409/8/2/179

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