Combination of Entner-Doudoroff pathway with MEP increases isoprene production in engineered Escherichia coli.

Combination of Entner-Doudoroff pathway with MEP increases isoprene production in engineered Escherichia coli.

Embden-Meyerhof pathway (EMP) in tandem with 2-C-methyl-D-erythritol 4-phosphate pathway (MEP) is commonly used for isoprenoid biosynthesis in E. coli. However, this combination has limitations as EMP generates an imbalanced distribution of pyruvate and glyceraldehyde-3-phosphate (G3P). Herein, four...

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Bibliographic Details
Main Authors: Huaiwei Liu, Yuanzhang Sun, Kristine Rose M Ramos, Grace M Nisola, Kris Niño G Valdehuesa, Won-Keun Lee, Si Jae Park, Wook-Jin Chung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869766?pdf=render

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http://europepmc.org/articles/PMC3869766?pdf=render

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