Multiple HPV-Induced Squamous Cell Carcinomas on the Fingers of a Patient with Systemic Lupus Erythematosus: A Case and Review

Multiple HPV-Induced Squamous Cell Carcinomas on the Fingers of a Patient with Systemic Lupus Erythematosus: A Case and Review

Human papilloma virus (HPV) infection is documented to be involved in the development of epithelial malignancies, mostly in cervical cancer. Systemic lupus erythematosus (SLE) patients have an increased prevalence of such an infection. We report the case of a 55-year-old female SLE patient who devel...

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Bibliographic Details
Main Authors: Georgios Nikolakis, Ioannis Karagiannidis, Vasiliki A. Zampeli, Andreas Altenburg, Martina Brunner, Christos C. Zouboulis
Format: Article
Language:English
Published: Karger Publishers 2015-11-01
Series:Case Reports in Dermatology
Subjects:
Human papilloma virus
Lupus erythematosus
Squamous cell carcinoma
HPV-33
Online Access:http://www.karger.com/Article/FullText/442017
Description
Summary:Human papilloma virus (HPV) infection is documented to be involved in the development of epithelial malignancies, mostly in cervical cancer. Systemic lupus erythematosus (SLE) patients have an increased prevalence of such an infection. We report the case of a 55-year-old female SLE patient who developed multiple in situ squamous cell carcinomas on her fingers, after chronic HPV infection. HPV-33 DNA was isolated from the lesions. The purpose of this case presentation is to raise awareness about HPV-induced malignancies for this high-risk group and propose an early HPV vaccination to efficiently prevent such comorbidities.
ISSN:1662-6567

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