Systematic Genetic Screens Reveal the Dynamic Global Functional Organization of the Bacterial Translation Machinery
Bacterial protein synthesis is an essential, conserved, and environmentally responsive process. Yet, many of its components and dependencies remain unidentified. To address this gap, we used quantitative synthetic genetic arrays to map functional relationships among >48,000 gene pairs in Escheric...
Main Authors: | Alla Gagarinova, Geordie Stewart, Bahram Samanfar, Sadhna Phanse, Carl A. White, Hiroyuki Aoki, Viktor Deineko, Natalia Beloglazova, Alexander F. Yakunin, Ashkan Golshani, Eric D. Brown, Mohan Babu, Andrew Emili |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-10-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124716312797 |
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