Scaling and Visualization of Nucleotide Sequences

• Main Authors: Stepanyan Ivan V., Khussein Abbakar M.
• Format: Article
• Language: English
• Published: EDP Sciences 2019-01-01
• Series: EPJ Web of Conferences
• Online Access: https://www.epj-conferences.org/articles/epjconf/pdf/2019/29/epjconf_mnps2018_03007.pdf

Algorithms for scaling and visualization of nucleotide sequences developed in this study allow identifying relationships between the biochemical parameters of DNA and RNA molecules with scale invariance, fractal clusters, nonlinear ordering and symmetry and noise immunity of visual representations in orthogonal coordinate systems. The algorithms are capable of displaying structures of the nucleotide sequences of living organisms by visualizing them in spaces of various dimensions and scales. Approximately one hundred genes (protozoa, plants, fungi, animals, viruses) were analysed and examples of visualization of the nucleotide composition of genomes of various species have been presented. The developed method contributes to an in-depth understanding of the principles of genetic coding and simplifying the perception of genetic information due to the algorithmic interpretation of the basic properties of polynucleotide fragments with visualization of the final geometric structure of the genetic code.