Stiff Person Syndrome Associated with Compartment Syndrome

Stiff person syndrome (SPS) is a rare and disabling neurological disorder of autoimmune origin, characterized by progressive stiffness and muscle spasms affecting the axial and limb muscles, most frequently associated with antibodies against glutamic acid decarboxylase. We describe a patient who pre...

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Bibliographic Details
Main Authors: Kok Pin Yong, Yew Long Lo
Format: Article
Language:English
Published: Karger Publishers 2019-07-01
Series:Case Reports in Neurology
Subjects:
Online Access:https://www.karger.com/Article/FullText/501793
Description
Summary:Stiff person syndrome (SPS) is a rare and disabling neurological disorder of autoimmune origin, characterized by progressive stiffness and muscle spasms affecting the axial and limb muscles, most frequently associated with antibodies against glutamic acid decarboxylase. We describe a patient who presented initially with compartment syndrome and was later diagnosed with SPS.This is the first case report of SPS possibly presenting initially with compartment syndrome. This case illustrates the importance of recognizing that patients with SPS may present with varied manifestations, including compartment syndrome, which by itself is a medical emergency.
ISSN:1662-680X