Nodular lesion in the tongue: A rare case of low grade myofibroblastic sarcoma

• Main Authors: Jefferson Rocha Tenório, Frederico Buhatem Medeiros, de Sousa Machado Suzana Cantanhede Orsini, dos Santos Pinto Décio Júnior
• Format: Article
• Language: English
• Published: Institute of Oncology, Sremska Kamenica, Serbia 2020-01-01
• Series: Archive of Oncology
• Subjects: immunohistochemistry; sarcoma; diagnosis; rare; tongue; neoplasms
• Online Access: https://scindeks-clanci.ceon.rs/data/pdf/0354-7310/2020/0354-73102002035J.pdf

Low grade myofibroblastic sarcoma is an atypical myofibroblastic malignant neoplasm that rarely affects the oral cavity and presents a challenging histological diagnosis. Here we report the case of a 38-year-old woman who had a nodular and symptomatic lesion on the lateral border of the tongue. After the biopsy, the histopathological analysis revealed a spindle cell lesion with fascicular and storiform pattern. We performed immunohistochemical analysis that showed intense labeling for vimentin, smooth muscle actin and moderate labeling for calponin and S-100. We emphasize the rarity of low grade myofibroblastic sarcoma such as a nodular lesion on the tongue and the need for accurate diagnosis.