Invitro Evaluation Of The Effect Of Fetal Hemoglobin Inducer Drugs On Proliferation And Differentiation Of Erythroid Progenitors With β -Thalassemia Gene Mutation

Invitro Evaluation Of The Effect Of Fetal Hemoglobin Inducer Drugs On Proliferation And Differentiation Of Erythroid Progenitors With β -Thalassemia Gene Mutation

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Background and Aim: Understanding the molecular mechanisms involved in the increased levels of HbF inducing drugs should be advised for effective induction. The aim of this study was to investigate the molecular effects of the drugs thalidomide and sodium butyrate considered as HbF inducer agents.  ...

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Bibliographic Details
Main Authors: Zahra Kashani Khatib, Ali Dehghanifard, Saeid Kaviani, Mehrdad Noruzinia, Momeneh Mohammadi, Fatemeh Mohammad Ali, Elham Roshandel, Sahar Mohammadi Fateh, Shaban Alizadeh
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2014-09-01
Series:پیاورد سلامت
Subjects:
thalidomide
sodium butyrate
erythroid precursors
cd71
cd235a
Online Access:http://payavard.tums.ac.ir/article-1-5505-en.html
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