Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex

Lipid antigens have been added to the antigenic repertoire in recent years. Here, the authors have identified Mamu-B*098 as a lipopeptide antigen presenting molecule and using structural and biochemical analysis have shown that it has a different antigen binding pocket to previously analysed protein...

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Bibliographic Details
Main Authors: Daisuke Morita, Yukie Yamamoto, Tatsuaki Mizutani, Takeshi Ishikawa, Juri Suzuki, Tatsuhiko Igarashi, Naoki Mori, Takashi Shiina, Hidetoshi Inoko, Hiroaki Fujita, Kazuhiro Iwai, Yoshimasa Tanaka, Bunzo Mikami, Masahiko Sugita
Format: Article
Language:English
Published: Nature Publishing Group 2016-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10356