Endothelial protein C receptor function in murine and human breast cancer development.

Several markers identify cancer stem cell-like populations, but little is known about the functional roles of stem cell surface receptors in tumor progression. Here, we show that the endothelial protein C receptor (EPCR), a stem cell marker in hematopoietic, neuronal and epithelial cells, is crucial...

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Bibliographic Details
Main Authors: Florence Schaffner, Naho Yokota, Tatiana Carneiro-Lobo, Maki Kitano, Michael Schaffer, G Mark Anderson, Barbara M Mueller, Charles T Esmon, Wolfram Ruf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3621887?pdf=render