5-(4-Chlorophenyl)-1-methyl-3-phenyl-3,6,8,9-tetrahydropyrazolo[3,4-b]thiopyrano[4,3-d]pyridine
The title compound, C22H18ClN3S, was synthesized by the reaction of 4-chlorobenzaldehyde, tetrahydrothiopyran-4-one and 3-methyl-1-phenyl-1H-pyrazol-5-amine in acetic acid without a catalyst. The pyridine and pyrazole rings are almost coplanar, the dihedral angle between their mean planes being 2.50...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2011-09-01
|
| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536811033514 |
| Summary: | The title compound, C22H18ClN3S, was synthesized by the reaction of 4-chlorobenzaldehyde, tetrahydrothiopyran-4-one and 3-methyl-1-phenyl-1H-pyrazol-5-amine in acetic acid without a catalyst. The pyridine and pyrazole rings are almost coplanar, the dihedral angle between their mean planes being 2.50 (1)°. The thiopyran ring exhibits an envelope conformation. The crystal packing is stabilized by intermolecular C—H...Cl hydrogen bonds and by C—H...π and π–π interactions [centroid–centroid distances of 3.825 (2) Å between pyridine rings and 3.557 (2) Å between pyrazole and pyridine rings. |
|---|---|
| ISSN: | 1600-5368 |