FGF21 promotes metabolic homeostasis via white adipose and leptin in mice.

Fibroblast growth factor 21 (FGF21) is a potent metabolic regulator, and pharmacological administration elicits glucose and lipid lowering responses in mammals. To delineate if adipose tissue is the predominant organ responsible for anti-diabetic effects of FGF21, we treated mice with reduced body f...

Full description

Bibliographic Details
Main Authors: Murielle M Véniant, Clarence Hale, Joan Helmering, Michelle M Chen, Shanaka Stanislaus, Jim Busby, Steven Vonderfecht, Jing Xu, David J Lloyd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3391219?pdf=render