Adipocyte progenitor cells initiate monocyte chemoattractant protein-1-mediated macrophage accumulation in visceral adipose tissue

Adipocyte progenitor cells initiate monocyte chemoattractant protein-1-mediated macrophage accumulation in visceral adipose tissue

Objective: Macrophages are important producers of obesity-induced MCP-1; however, initial obesity-induced increases in MCP-1 production precede M1 macrophage accumulation in visceral adipose tissue (VAT). The initial cellular source of obesity-induced MCP-1 in vivo is currently unknown. Preliminary...

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Bibliographic Details
Main Authors: Jennifer L. Kaplan, Melissa A. Marshall, Chantel C. McSkimming, Daniel B. Harmon, James C. Garmey, Stephanie N. Oldham, Peter Hallowell, Coleen A. McNamara
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Molecular Metabolism
Subjects:
Obesity
MCP-1
Id3
Adipocyte progenitors
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877815001441

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