Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni

Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni

Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in co...

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Bibliographic Details
Main Authors: Lílian Beck, Daniele SM Van-Lüme, Joelma R de Souza, Clarice N Lins de Morais, Wlademir G Melo, Edeneide Xavier, Constança S Barbosa, Marcílio L Aroucha, Ana Lúcia C Domingues, Tereza Favre, Otávio Pieri, Frederico GC Abath, Silvia ML Montenegro
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2004-08-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
keyhole limpet haemocyanin
soluble egg antigens
enzime-linked immunosorbent assay
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000900017

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