Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni

Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in co...

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Main Authors: Lílian Beck, Daniele SM Van-Lüme, Joelma R de Souza, Clarice N Lins de Morais, Wlademir G Melo, Edeneide Xavier, Constança S Barbosa, Marcílio L Aroucha, Ana Lúcia C Domingues, Tereza Favre, Otávio Pieri, Frederico GC Abath, Silvia ML Montenegro
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2004-08-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000900017
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spelling doaj-da878d2649aa4869946abc0d35c0f9582020-11-24T23:54:20ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.0074-02761678-80602004-08-0199979810.1590/S0074-02762004000900017Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoniLílian BeckDaniele SM Van-LümeJoelma R de SouzaClarice N Lins de MoraisWlademir G MeloEdeneide XavierConstança S BarbosaMarcílio L ArouchaAna Lúcia C DominguesTereza FavreOtávio PieriFrederico GC AbathSilvia ML MontenegroSpecific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000900017keyhole limpet haemocyaninsoluble egg antigensenzime-linked immunosorbent assay
collection DOAJ
language English
format Article
sources DOAJ
author Lílian Beck
Daniele SM Van-Lüme
Joelma R de Souza
Clarice N Lins de Morais
Wlademir G Melo
Edeneide Xavier
Constança S Barbosa
Marcílio L Aroucha
Ana Lúcia C Domingues
Tereza Favre
Otávio Pieri
Frederico GC Abath
Silvia ML Montenegro
spellingShingle Lílian Beck
Daniele SM Van-Lüme
Joelma R de Souza
Clarice N Lins de Morais
Wlademir G Melo
Edeneide Xavier
Constança S Barbosa
Marcílio L Aroucha
Ana Lúcia C Domingues
Tereza Favre
Otávio Pieri
Frederico GC Abath
Silvia ML Montenegro
Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni
Memórias do Instituto Oswaldo Cruz.
keyhole limpet haemocyanin
soluble egg antigens
enzime-linked immunosorbent assay
author_facet Lílian Beck
Daniele SM Van-Lüme
Joelma R de Souza
Clarice N Lins de Morais
Wlademir G Melo
Edeneide Xavier
Constança S Barbosa
Marcílio L Aroucha
Ana Lúcia C Domingues
Tereza Favre
Otávio Pieri
Frederico GC Abath
Silvia ML Montenegro
author_sort Lílian Beck
title Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni
title_short Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni
title_full Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni
title_fullStr Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni
title_full_unstemmed Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni
title_sort evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni
publisher Instituto Oswaldo Cruz, Ministério da Saúde
series Memórias do Instituto Oswaldo Cruz.
issn 0074-0276
1678-8060
publishDate 2004-08-01
description Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis.
topic keyhole limpet haemocyanin
soluble egg antigens
enzime-linked immunosorbent assay
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000900017
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