Chitosan-graft-branched polyethylenimine copolymers: influence of degree of grafting on transfection behavior.

Chitosan-graft-branched polyethylenimine copolymers: influence of degree of grafting on transfection behavior.

BACKGROUND: Successful non-viral gene delivery currently requires compromises to achieve useful transfection levels while minimizing toxicity. Despite high molecular weight (MW) branched polyethylenimine (bPEI) is considered the gold standard polymeric transfectant, it suffers from high cytotoxicity...

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Bibliographic Details
Main Authors: Daniele Pezzoli, Francesca Olimpieri, Chiara Malloggi, Sabrina Bertini, Alessandro Volonterio, Gabriele Candiani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3324502?pdf=render

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