Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of MitoKATP in Energy Homeostasis

Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of MitoKATP in Energy Homeostasis

Mitochondrial ATP-sensitive potassium channel (mitoKATP) is a common end effector of many protective stimuli in myocardial ischemia-reperfusion injury (MIRI). However, the specific molecular mechanism underlying its myocardial protective effect is not well elucidated. We characterized an anoxia/reox...

Full description

Bibliographic Details
Main Authors:	Song Cao, Yun Liu, Wenting Sun, Li Zhao, Lin Zhang, Xinkui Liu, Tian Yu
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2015/756576

Similar Items

PI3K–AKT Pathway Protects Cardiomyocytes Against Hypoxia-Induced Apoptosis by MitoKATP-Mediated Mitochondrial Translocation of pAKT
by: Hua-Pei Song, et al.
Published: (2018-08-01)

Preliminary Characterization of Mitochondrial ATP-sensitive Potassium Channel (MitoKATP) Activity in Mouse Heart Mitochondria
by: Aachi, Venkat Raghav
Published: (2009)

Downregulation of TSPO expression inhibits oxidative stress and maintains mitochondrial homeostasis in cardiomyocytes subjected to anoxia/reoxygenation injury
by: Yan Meng, et al.
Published: (2020-01-01)

The role of AMPKα2 in cardiomyocytes anoxia/reoxygenation injury mediated by Cl<sup>-</sup>
by: Liu Dan, et al.
Published: (2012-10-01)

Ischemic postconditioning and pinacidil suppress calcium overload in anoxia-reoxygenation cardiomyocytes via down-regulation of the calcium-sensing receptor
by: Lin Zhang, et al.
Published: (2016-11-01)

Studies on Protective Actions of Levosimendan in Human Progenitor Cell-Derived Cardiomyocytes after Anoxia- Reoxygenation
by: Li, Ping-Chun, et al.
Published: (2014)

Capsaicin Protects Cardiomyocytes against Anoxia/Reoxygenation Injury via Preventing Mitochondrial Dysfunction Mediated by SIRT1
by: Huan He, et al.
Published: (2017-01-01)

IL-33 attenuates anoxia/reoxygenation-induced cardiomyocyte apoptosis by inhibition of PKCβ/JNK pathway.
by: Tao Rui, et al.
Published: (2013-01-01)

Inhibition of reverse-mode sodium-calcium exchanger activity and apoptosis by levosimendan in human cardiomyocyte progenitor cell-derived cardiomyocytes after anoxia and reoxygenation.
by: Ping-Chun Li, et al.
Published: (2014-01-01)

Protective Effect and Mechanism of Total Flavones from Rhododendron simsii Planch Flower on Cultured Rat Cardiomyocytes with Anoxia and Reoxygenation
by: Yi Jiao, et al.
Published: (2015-01-01)

Investigation of molecular and metabolic events in response to anoxia-reoxygenation in Arabidopsis
by: Kuen-Jin Tsai, et al.
Published: (2015)

Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries.
by: Paul Vigne, et al.
Published: (2009-01-01)

Histone deacetylase inhibitors modulate KATP subunit transcription in HL-1 cardiomyocytes through effects on cholesterol homeostasis
by: Naheed eFatima, et al.
Published: (2015-08-01)

Anoxia, plasma membrane structure and calcium homeostasis : photobleaching and microfluorescence spectroscopic investigations in isolated rat cardiomyocytes
by: Sowerby, Andrew John
Published: (1991)

Postconditioning Protection Against Myocardiocyte Anoxia/Reoxygenation Injury From Penehyclidine Hydrochloride
by: Ren JY, et al.
Published: (2019-11-01)

Role of PON in anoxia-reoxygenation injury: a Drosophila melanogaster transgenic model.
by: Juan Carlos Caraballo, et al.
Published: (2014-01-01)

MitoNEET Protects HL-1 Cardiomyocytes from Oxidative Stress Mediated Apoptosis in an In Vitro Model of Hypoxia and Reoxygenation.
by: Anika Habener, et al.
Published: (2016-01-01)

Genome-Wide Association Analysis of Anoxia Tolerance in Drosophila melanogaster
by: Jacob B. Campbell, et al.
Published: (2019-09-01)

Protective effect of astragalus injection against anoxia-reoxygenation injury in human umbilical vein endothelial cells
by: YAO He, et al.
Published: (2020-10-01)

Changes of mitochondrial pathway in hypoxia/reoxygenation induced cardiomyocytes apoptosis.
by: Tielong Chen, et al.
Published: (2008-01-01)

Physiopathologie du cœur embryonnaire soumis à l'anoxie-réoxygénation: Rôle protecteur du NO et des canaux KATP.
by: Sarre, Alexandre
Published: (2006)

Transient receptor potential melastatin-4 is involved in hypoxia-reoxygenation injury in the cardiomyocytes.
by: Hulin Piao, et al.
Published: (2015-01-01)

Lupanine Improves Glucose Homeostasis by Influencing KATP Channels and Insulin Gene Expression
by: Mats Wiedemann, et al.
Published: (2015-10-01)

Newborn hypoxia/anoxia inhibits cardiomyocyte proliferation and decreases cardiomyocyte endowment in the developing heart: role of endothelin-1.
by: Alexandra N Paradis, et al.
Published: (2015-01-01)

The effect of hypoxia and reoxygenation on STAT3 regulation in potential cardiomyocyte models
by: Evans, Emma Louise
Published: (2012)

Myricitrin Protects Cardiomyocytes from Hypoxia/Reoxygenation Injury: Involvement of Heat Shock Protein 90
by: Min Wang, et al.
Published: (2017-06-01)

MitosRNAs and extreme anoxia tolerance in embryos of the annual killifish Austrofundulus limnaeus
by: Claire L. Riggs, et al.
Published: (2019-12-01)

Genome-wide CRISPR/Cas9 screening in human iPS derived cardiomyocytes uncovers novel mediators of doxorubicin cardiotoxicity
by: Valerie Sapp, et al.
Published: (2021-07-01)

Calreticulin Translocation Aggravates Endoplasmic Reticulum Stress-associated Apoptosis during Cardiomyocyte Hypoxia/Reoxygenation
by: Fei-Fei Xu, et al.
Published: (2015-01-01)

miR-16-5p Regulates PTPN4 and Affects Cardiomyocyte Apoptosis and Autophagy Induced by Hypoxia/Reoxygenation
by: Zheng Cao, et al.
Published: (2021-01-01)

Poloxamer 188 Protects Isolated Adult Mouse Cardiomyocytes from Reoxygenation Injury
by: Michele M. Salzman, et al.
Published: (2020-12-01)

Atherogenic L5 LDL induces cardiomyocyte apoptosis and inhibits KATP channels through CaMKII activation
by: Yanzhuo Ma, et al.
Published: (2020-08-01)

The Metabolomic Response of Crucian Carp (<i>Carassius carassius)</i> to Anoxia and Reoxygenation Differs between Tissues and Hints at Uncharacterized Survival Strategies
by: Helge-Andre Dahl, et al.
Published: (2021-07-01)

Factors that May Protect the Native Hibernator Syrian Hamster Renal Tubular Epithelial Cells from Ferroptosis Due to Warm Anoxia-Reoxygenation
by: Theodoros Eleftheriadis, et al.
Published: (2019-03-01)

TEMPERATURE MODULATION OF THE EFFECTS OF REPETITIVE ANOXIA ON POTASSIUM HOMEOSTASIS IN THE BRAIN OF Drosophila melanogaster
by: RODRIGUEZ PINTO, ESTEBAN
Published: (2012)

Anoxia
Published: (2012)

XuefuZhuyu decoction protected cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy
by: Xiaowen Shi, et al.
Published: (2017-06-01)

Overexpression of miR-375 Protects Cardiomyocyte Injury following Hypoxic-Reoxygenation Injury
by: Md Sayed Ali Sheikh
Published: (2020-01-01)

Sevoflurane postconditioning attenuates cardiomyocyte hypoxia/reoxygenation injury via restoring mitochondrial morphology
by: Jin Yu, et al.
Published: (2016-11-01)

Cyclophilin A Protects Cardiomyocytes against Hypoxia/Reoxygenation-Induced Apoptosis via the AKT/Nox2 Pathway
by: Fuyu Cheng, et al.
Published: (2019-01-01)