Toward a Better Understanding of the Role of Helicobacter pylori Infection as a Cause of Dyspepsia

The relationship between gastric inflammation caused by Helicobacter pylori infection and symptoms of dyspepsia remains controversial (1). Using a murine model of gastric infection, Bercik et al provide new insights into the mechanism underlying such interactions. Gastric sections from Balb/c mi...

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Main Authors:	Frank YH Lin, Philip M Sherman
Format:	Article
Language:	English
Published:	Hindawi Limited 2004-01-01
Series:	Canadian Journal of Gastroenterology
Online Access:	http://dx.doi.org/10.1155/2004/637534

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spelling	doaj-da786ea1bd0f44cfabc0999f445ca9ed2020-11-24T23:05:09ZengHindawi LimitedCanadian Journal of Gastroenterology0835-79002004-01-0118213613710.1155/2004/637534Toward a Better Understanding of the Role of Helicobacter pylori Infection as a Cause of DyspepsiaFrank YH LinPhilip M ShermanThe relationship between gastric inflammation caused by Helicobacter pylori infection and symptoms of dyspepsia remains controversial (1). Using a murine model of gastric infection, Bercik et al provide new insights into the mechanism underlying such interactions. Gastric sections from Balb/c mice infected with H pylori, strain SS-1, were used for both histological evaluation and studies of neuromuscular physiology. Acute infection (two weeks) caused an antral-predominant polymorphonuclear cell infiltrate that was superceded by a corpus-predominant mononuclear and macrophage infiltrate in chronic infection (three to 16 months).http://dx.doi.org/10.1155/2004/637534
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Frank YH Lin Philip M Sherman
spellingShingle	Frank YH Lin Philip M Sherman Toward a Better Understanding of the Role of Helicobacter pylori Infection as a Cause of Dyspepsia Canadian Journal of Gastroenterology
author_facet	Frank YH Lin Philip M Sherman
author_sort	Frank YH Lin
title	Toward a Better Understanding of the Role of Helicobacter pylori Infection as a Cause of Dyspepsia
title_short	Toward a Better Understanding of the Role of Helicobacter pylori Infection as a Cause of Dyspepsia
title_full	Toward a Better Understanding of the Role of Helicobacter pylori Infection as a Cause of Dyspepsia
title_fullStr	Toward a Better Understanding of the Role of Helicobacter pylori Infection as a Cause of Dyspepsia
title_full_unstemmed	Toward a Better Understanding of the Role of Helicobacter pylori Infection as a Cause of Dyspepsia
title_sort	toward a better understanding of the role of helicobacter pylori infection as a cause of dyspepsia
publisher	Hindawi Limited
series	Canadian Journal of Gastroenterology
issn	0835-7900
publishDate	2004-01-01
description	The relationship between gastric inflammation caused by Helicobacter pylori infection and symptoms of dyspepsia remains controversial (1). Using a murine model of gastric infection, Bercik et al provide new insights into the mechanism underlying such interactions. Gastric sections from Balb/c mice infected with H pylori, strain SS-1, were used for both histological evaluation and studies of neuromuscular physiology. Acute infection (two weeks) caused an antral-predominant polymorphonuclear cell infiltrate that was superceded by a corpus-predominant mononuclear and macrophage infiltrate in chronic infection (three to 16 months).
url	http://dx.doi.org/10.1155/2004/637534
work_keys_str_mv	AT frankyhlin towardabetterunderstandingoftheroleofhelicobacterpyloriinfectionasacauseofdyspepsia AT philipmsherman towardabetterunderstandingoftheroleofhelicobacterpyloriinfectionasacauseofdyspepsia
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Toward a Better Understanding of the Role of Helicobacter pylori Infection as a Cause of Dyspepsia

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