Targeting Inhibition of SmpB by Peptide Aptamer Attenuates the Virulence to Protect Zebrafish against Aeromonas veronii Infection

Targeting Inhibition of SmpB by Peptide Aptamer Attenuates the Virulence to Protect Zebrafish against Aeromonas veronii Infection

Aeromonas veronii is an important pathogen of aquatic animals, wherein Small protein B (SmpB) is required for pathogenesis by functioning as both a component in stalled-ribosome rescue and a transcription factor in upregulation of virulence gene bvgS expression. Here a specific peptide aptamer PA-1...

Full description

Bibliographic Details
Main Authors: Peng Liu, Dongyi Huang, Xinwen Hu, Yanqiong Tang, Xiang Ma, Rihui Yan, Qian Han, Jianchun Guo, Yueling Zhang, Qun Sun, Zhu Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Microbiology
Subjects:
Aeromonas veronii
SmpB
bacterial two-hybrid system
selection of peptide aptamers library
live attenuated vaccines
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01766/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01766/full

Similar Items