Malaria real-time PCR: correlation with clinical presentation

Among 112 patients infected only by Plasmodium falciparum, WHO criteria of severity were compared with parasite load assessed by microscopy and quantitative PCR. Clinical severity was significantly correlated with higher parasite load as determined by microscopy (p < 0.001) and by PCR (p < 0.0...

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Main Authors:	L. Dormond, K. Jaton, S. de Vallière, B. Genton, G. Greub
Format:	Article
Language:	English
Published:	Elsevier 2015-05-01
Series:	New Microbes and New Infections
Subjects:	Diagnosis disease severity malaria microscopy Plasmodium falciparum real-time PCR
Online Access:	http://www.sciencedirect.com/science/article/pii/S2052297515000268

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spelling	doaj-da6cf7ab323d4fdfa31eac9b8f95ffd92020-11-25T01:33:51ZengElsevierNew Microbes and New Infections2052-29752015-05-015C101210.1016/j.nmni.2015.02.004Malaria real-time PCR: correlation with clinical presentationL. Dormond0K. Jaton1S. de Vallière2B. Genton3G. Greub4Institute of Microbiology, University Hospital Centre and University of Lausanne, Lausanne, SwitzerlandInstitute of Microbiology, University Hospital Centre and University of Lausanne, Lausanne, SwitzerlandTravel Clinic, Department of Ambulatory Care and Community Medicine, University Hospital, Lausanne, SwitzerlandTravel Clinic, Department of Ambulatory Care and Community Medicine, University Hospital, Lausanne, SwitzerlandInstitute of Microbiology, University Hospital Centre and University of Lausanne, Lausanne, SwitzerlandAmong 112 patients infected only by Plasmodium falciparum, WHO criteria of severity were compared with parasite load assessed by microscopy and quantitative PCR. Clinical severity was significantly correlated with higher parasite load as determined by microscopy (p < 0.001) and by PCR (p < 0.001). Hence, quantitative PCR might be useful to predict outcome.http://www.sciencedirect.com/science/article/pii/S2052297515000268Diagnosisdisease severitymalariamicroscopyPlasmodium falciparumreal-time PCR
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	L. Dormond K. Jaton S. de Vallière B. Genton G. Greub
spellingShingle	L. Dormond K. Jaton S. de Vallière B. Genton G. Greub Malaria real-time PCR: correlation with clinical presentation New Microbes and New Infections Diagnosis disease severity malaria microscopy Plasmodium falciparum real-time PCR
author_facet	L. Dormond K. Jaton S. de Vallière B. Genton G. Greub
author_sort	L. Dormond
title	Malaria real-time PCR: correlation with clinical presentation
title_short	Malaria real-time PCR: correlation with clinical presentation
title_full	Malaria real-time PCR: correlation with clinical presentation
title_fullStr	Malaria real-time PCR: correlation with clinical presentation
title_full_unstemmed	Malaria real-time PCR: correlation with clinical presentation
title_sort	malaria real-time pcr: correlation with clinical presentation
publisher	Elsevier
series	New Microbes and New Infections
issn	2052-2975
publishDate	2015-05-01
description	Among 112 patients infected only by Plasmodium falciparum, WHO criteria of severity were compared with parasite load assessed by microscopy and quantitative PCR. Clinical severity was significantly correlated with higher parasite load as determined by microscopy (p < 0.001) and by PCR (p < 0.001). Hence, quantitative PCR might be useful to predict outcome.
topic	Diagnosis disease severity malaria microscopy Plasmodium falciparum real-time PCR
url	http://www.sciencedirect.com/science/article/pii/S2052297515000268
work_keys_str_mv	AT ldormond malariarealtimepcrcorrelationwithclinicalpresentation AT kjaton malariarealtimepcrcorrelationwithclinicalpresentation AT sdevalliere malariarealtimepcrcorrelationwithclinicalpresentation AT bgenton malariarealtimepcrcorrelationwithclinicalpresentation AT ggreub malariarealtimepcrcorrelationwithclinicalpresentation
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Malaria real-time PCR: correlation with clinical presentation

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