Malaria real-time PCR: correlation with clinical presentation

Malaria real-time PCR: correlation with clinical presentation

Among 112 patients infected only by Plasmodium falciparum, WHO criteria of severity were compared with parasite load assessed by microscopy and quantitative PCR. Clinical severity was significantly correlated with higher parasite load as determined by microscopy (p < 0.001) and by PCR (p < 0.0...

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Bibliographic Details
Main Authors: L. Dormond, K. Jaton, S. de Vallière, B. Genton, G. Greub
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:New Microbes and New Infections
Subjects:
Diagnosis
disease severity
malaria
microscopy
Plasmodium falciparum
real-time PCR
Online Access:http://www.sciencedirect.com/science/article/pii/S2052297515000268
Description
Summary:Among 112 patients infected only by Plasmodium falciparum, WHO criteria of severity were compared with parasite load assessed by microscopy and quantitative PCR. Clinical severity was significantly correlated with higher parasite load as determined by microscopy (p < 0.001) and by PCR (p < 0.001). Hence, quantitative PCR might be useful to predict outcome.
ISSN:2052-2975

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