Anti-Inflammatory and Antitumor Effects of Hydroxytyrosol but Not Oleuropein on Experimental Glioma In Vivo. A Putative Role for the Renin-Angiotensin System

Anti-Inflammatory and Antitumor Effects of Hydroxytyrosol but Not Oleuropein on Experimental Glioma In Vivo. A Putative Role for the Renin-Angiotensin System

Functional roles of the angiotensin peptides of the renin-angiotensin system (RAS) cascade can be analyzed through their corresponding proteolytic regulatory enzymes aspartyl aminopeptidase (ASAP), aminopeptidase A (APA), aminopeptidase B (APB), aminopeptidase N (APN) and insulin-regulated aminopept...

Full description

Bibliographic Details
Main Authors:	María Jesús Ramírez-Expósito, José Manuel Martínez-Martos
Format:	Article
Language:	English
Published:	MDPI AG 2018-01-01
Series:	Biomedicines
Subjects:	oleuropein hydroxytyrosol glioma C6 renin-angiotensin system aminopeptidase inflammation
Online Access:	http://www.mdpi.com/2227-9059/6/1/11

Similar Items

Phenolic compounds oleuropein and hydroxytyrosol exert differential effects on glioma development via antioxidant defense systems
by: José Manuel Martínez-Martos, et al.
Published: (2014-11-01)

Hydroxytyrosol and Oleuropein-Enriched Extracts Obtained from Olive Oil Wastes and By-Products as Active Antioxidant Ingredients for Poly (Vinyl Alcohol)-Based Films
by: Francesca Luzi, et al.
Published: (2021-04-01)

Enzymatic Conversion of Oleuropein to Hydroxytyrosol Using Immobilized <i>β</i>-Glucosidase on Porous Carbon Cuboids
by: Alexandra V. Chatzikonstantinou, et al.
Published: (2019-08-01)

Protective effects of olive oil phenolics oleuropein and hydroxytyrosol against hydrogen peroxide-induced DNA damage in human peripheral lymphocytes
by: Zorić Nataša, et al.
Published: (2021-03-01)

The Olive Biophenols Oleuropein and Hydroxytyrosol Selectively Reduce Proliferation, Influence the Cell Cycle, and Induce Apoptosis in Pancreatic Cancer Cells
by: Chloe D. Goldsmith, et al.
Published: (2018-07-01)

Enzymatic Hydrolysis of Oleuropein from Olea europea (Olive) Leaf Extract and Antioxidant Activities
by: Jiao-Jiao Yuan, et al.
Published: (2015-02-01)

Hydroxytyrosol, Tyrosol and Derivatives and Their Potential Effects on Human Health
by: Ana Karković Marković, et al.
Published: (2019-05-01)

Cellular Antioxidant Effects and Bioavailability of Food Supplements Rich in Hydroxytyrosol
by: Cecilia Bender, et al.
Published: (2021-05-01)

The Type of Fat in the Diet Influences the Behavior and the Relationship Between Cystinyl and Alanyl Aminopeptidase Activities in Frontal Cortex, Liver, and Plasma
by: Ana Belén Segarra, et al.
Published: (2020-05-01)

Regulation of Male Fertility by the Renin-Angiotensin System
by: Marta Gianzo, et al.
Published: (2020-10-01)

Capacities of laboratory diagnosis in the assessment of the activity of the renin-angiotensin-aldosterone system
by: M L Maksimov
Published: (2010-06-01)

Hydroxytyrosol in the Prevention of the Metabolic Syndrome and Related Disorders
by: Julien Peyrol, et al.
Published: (2017-03-01)

Expression of Components of the Renin-Angiotensin System by the Putative Stem Cell Population Within WHO Grade I Meningioma
by: Ganeshwaran Shivapathasundram, et al.
Published: (2019-05-01)

RENIN-ANGIOTENSIN SYSTEM IN REGULATION OF HEMATOPOIESIS
by: M. L. Kanaeva, et al.
Published: (2018-02-01)

Differential absorption and metabolism of hydroxytyrosol and its precursors oleuropein and secoiridoids
by: María-Carmen López de las Hazas, et al.
Published: (2016-04-01)

Thyroid Disorders Change the Pattern of Response of Angiotensinase Activities in the Hypothalamus-Pituitary-Adrenal Axis of Male Rats
by: Ana B. Segarra, et al.
Published: (2018-11-01)

The clinical relevance of local renin angiotensin systems
by: Duncan John Campbell
Published: (2014-07-01)

Evaluation of Systemic Renin and Angiotensin II Levels in Normal Tension Glaucoma
by: Soo Ji Jeon, et al.
Published: (2020-11-01)

The renin-angiotensin system and immune function
by: Groeschel, Michael
Published: (2009)

From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase
by: Mathias Hallberg, et al.
Published: (2020-10-01)

Renin–angiotensin system inhibition in COVID-19 patients: Friend or foe?
by: Bilgehan Karadağ
Published: (2020-07-01)

Renin- angiotensin system in control of vascular reactivity
by: I. Drenjančević-Perić, et al.
Published: (2006-02-01)

EFFECTS OF VITAMIN D ON THE RENIN-ANGIOTENSIN SYSTEM
by: L. Pashova-Stoyanova, et al.
Published: (2019-09-01)

The renin-angiotensin system and its blockers
by: Igić Rajko, et al.
Published: (2014-01-01)

Therapeutic targets of renin-angiotensin system in ocular disorders
by: Rajesh Choudhary, et al.
Published: (2017-03-01)

Expression of renin–angiotensin system (RAS) components in endometrial cancer
by: Sarah J Delforce, et al.
Published: (2017-02-01)

Editorial: The Role of the Renin-Angiotensin System in the Central Nervous System
by: Natalia P. Rocha, et al.
Published: (2021-07-01)

Effects of Statins on Renin–Angiotensin System
by: Nasim Kiaie, et al.
Published: (2021-07-01)

Renin-angiotensin-aldosterone system in the elderly: rational use of aliskiren in managing hypertension
by: Karl Andersen
Published: (2009-03-01)

Renin angiotensin aldosterone system in anaphylactic reactions induced by immunotherapy
by: Mehmet Karaayvaz, et al.
Published: (1998-01-01)

The Effect of Moderate Hypothermia on Renin-Angiotensin – Aldosterone System in Male Rats
by: Masoumeh Kourosh Arami, et al.
Published: (2004-06-01)

Expression of the Components of the Renin-Angiotensin System in Venous Malformation
by: Sam eSiljee, et al.
Published: (2016-05-01)

The renin–angiotensin system: a possible new target for depression
by: João Vian, et al.
Published: (2017-08-01)

Effects of renin-angiotensin system inhibitors on pancreatic injury in cerulein-induced acute pancreatitis: potential role of pancreatic renin-angiotensin system in exocrine pancreas.
Published: (2003)

Reduced plasma levels of angiotensin-(1-7) and renin activity in preeclamptic patients are associated with the angiotensin I- converting enzyme deletion/deletion genotype
by: E.P. Velloso, et al.

Reduced plasma levels of angiotensin-(1-7) and renin activity in preeclamptic patients are associated with the angiotensin I- converting enzyme deletion/deletion genotype
by: E.P. Velloso, et al.
Published: (2007-04-01)

Effects of Resveratrol on the Renin-Angiotensin System in the Aging Kidney
by: In-Ae Jang, et al.
Published: (2018-11-01)

Expression of Components of the Renin-Angiotensin System by Cancer Stem Cells in Renal Clear Cell Carcinoma
by: Sam Siljee, et al.
Published: (2021-04-01)

Effect of Ramipril on Renin-Angiotensin-Aldosterone System of Young and Middle-Aged Patients with Hypertension
by: Hui-Ling Yuan
Published: (2020-12-01)

Polymorphisms of the renin-angiotensin system are not associated with overweight and obesity in a general adult population
by: Deborah de Farias Lelis, et al.