Improper tagging of the non-essential small capsid protein VP26 impairs nuclear capsid egress of herpes simplex virus.

Improper tagging of the non-essential small capsid protein VP26 impairs nuclear capsid egress of herpes simplex virus.

To analyze the subcellular trafficking of herpesvirus capsids, the small capsid protein has been labeled with different fluorescent proteins. Here, we analyzed the infectivity of several HSV1(17(+)) strains in which the N-terminal region of the non-essential small capsid protein VP26 had been tagged...

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Bibliographic Details
Main Authors: Claus-Henning Nagel, Katinka Döhner, Anne Binz, Rudolf Bauerfeind, Beate Sodeik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3432071?pdf=render

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