Tenuifolide B from Cinnamomum tenuifolium Stem Selectively Inhibits Proliferation of Oral Cancer Cells via Apoptosis, ROS Generation, Mitochondrial Depolarization, and DNA Damage

Tenuifolide B from Cinnamomum tenuifolium Stem Selectively Inhibits Proliferation of Oral Cancer Cells via Apoptosis, ROS Generation, Mitochondrial Depolarization, and DNA Damage

The development of drugs that selectively kill oral cancer cells but are less harmful to normal cells still provide several challenges. In this study, the antioral cancer effects of tenuifolide B (TFB), extracted from the stem of the plant Cinnamomum tenuifolium are evaluated in terms of their effec...

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Bibliographic Details
Main Authors: Chung-Yi Chen, Ching-Yu Yen, Hui-Ru Wang, Hui-Ping Yang, Jen-Yang Tang, Hurng-Wern Huang, Shih-Hsien Hsu, Hsueh-Wei Chang
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Toxins
Subjects:
selective killing
oral cancer
natural product
apoptosis
ROS
DNA damage
Online Access:http://www.mdpi.com/2072-6651/8/11/319

Internet

http://www.mdpi.com/2072-6651/8/11/319

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