ENZYMATIC ACTIVITY OF COMPONENTS OF ENERGY SUPPLY SYSTEM OF MITOCHONDRIES OF PERIPHERAL BLOOD LEUKOCYTES IN DYNAMICS OF GERENA’S CARCINOMA GROWTH

The NАDН-dehydrogenase, succinatedehydrogenase and cytochromoxidase activities of mitochondries of blood peripheral leukocytes were studied in rats with transplanted Gerena’s carcinoma. It was shown that in dynamics of Gerena’s carcinoma growth, NАDН-dehydrogenase activity was inhibited, while succi...

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Bibliographic Details
Main Authors: O. N. Voloschuk, M. M. Marchenko
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2016-02-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
Online Access:https://www.siboncoj.ru/jour/article/view/252
Description
Summary:The NАDН-dehydrogenase, succinatedehydrogenase and cytochromoxidase activities of mitochondries of blood peripheral leukocytes were studied in rats with transplanted Gerena’s carcinoma. It was shown that in dynamics of Gerena’s carcinoma growth, NАDН-dehydrogenase activity was inhibited, while succinate dehydrogenase activity was activated. The level of cytochromoxidase activity remained within the control values at the terminal stage of tumor growth
ISSN:1814-4861
2312-3168