Time-Course Effects of Acute Aflatoxin B1 Exposure on Hepatic Mitochondrial Lipids and Oxidative Stress in Rats

Time-Course Effects of Acute Aflatoxin B1 Exposure on Hepatic Mitochondrial Lipids and Oxidative Stress in Rats

Aflatoxins are secondary metabolites of certain Aspergillus species, that contaminate staple foods, particularly in developing countries. Aflatoxin B1 (AFB1) is the most toxic and common of the major types of aflatoxins. AFB1 is hepatotoxic and has been implicated in increasing the risk of hepatocel...

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Bibliographic Details
Main Authors: Oluwakemi A. Rotimi, Solomon O. Rotimi, Jaclyn M. Goodrich, Isaacson B. Adelani, Emmanuel Agbonihale, Gbemisola Talabi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Pharmacology
Subjects:
aflatoxin B1
liver
mitochondria
lipid
cholesterol
thioredoxin reductase
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00467/full

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