Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate

Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate

A quaternary ammonium salt was synthesized from diethylaminoethyl methacrylate (DEAEMA) by quaternization with hexadecyl bromide. The resultant compound (Am-h) was characterized by FTIR and NMR spectroscopy. Its bactericidal activity was evaluated by determining minimum inhibitory concentration (MIC...

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Main Authors: Makhloufia Mohammed, BenaÏssa Tahar, Derdour AÏcha, Henni Djamel Eddine
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2010/637549
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spelling doaj-da2e774e7668464abbbe82fe0031aa372020-11-24T21:30:08ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102010-01-017S1S61S6610.1155/2010/637549Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl MethacrylateMakhloufia Mohammed0BenaÏssa Tahar1Derdour AÏcha2Henni Djamel Eddine3Physical Chemistry Studies Laboratory University of Dr. Moulay Tahar, Saïda – 20000, AlgeriaPhysical Chemistry Studies Laboratory University of Dr. Moulay Tahar, Saïda – 20000, AlgeriaApplied Organic Chemistry Laboratory, University of Esénia, Oran-31000, AlgeriaPhytopathology Laboratory, University of Esénia, Oran-31000, AlgeriaA quaternary ammonium salt was synthesized from diethylaminoethyl methacrylate (DEAEMA) by quaternization with hexadecyl bromide. The resultant compound (Am-h) was characterized by FTIR and NMR spectroscopy. Its bactericidal activity was evaluated by determining minimum inhibitory concentration (MIC) values and inhibitory zone diameter against gram positive bacteria (Streptococcus sp.) and gram negative bacteria such as Acenito baumannii, Klebsiella pneumoniae and Proteus sp. respectively. The results showed that the MIC values of the synthesised compound (Am-h) were 2 μg/mL against Acenito baumannii, Klebsiella pneumoniae, Proteus sp. and Streptococcus sp.http://dx.doi.org/10.1155/2010/637549
collection DOAJ
language English
format Article
sources DOAJ
author Makhloufia Mohammed
BenaÏssa Tahar
Derdour AÏcha
Henni Djamel Eddine
spellingShingle Makhloufia Mohammed
BenaÏssa Tahar
Derdour AÏcha
Henni Djamel Eddine
Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate
E-Journal of Chemistry
author_facet Makhloufia Mohammed
BenaÏssa Tahar
Derdour AÏcha
Henni Djamel Eddine
author_sort Makhloufia Mohammed
title Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate
title_short Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate
title_full Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate
title_fullStr Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate
title_full_unstemmed Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate
title_sort antibacterial activity of quaternary ammonium salt from diethylaminoethyl methacrylate
publisher Hindawi Limited
series E-Journal of Chemistry
issn 0973-4945
2090-9810
publishDate 2010-01-01
description A quaternary ammonium salt was synthesized from diethylaminoethyl methacrylate (DEAEMA) by quaternization with hexadecyl bromide. The resultant compound (Am-h) was characterized by FTIR and NMR spectroscopy. Its bactericidal activity was evaluated by determining minimum inhibitory concentration (MIC) values and inhibitory zone diameter against gram positive bacteria (Streptococcus sp.) and gram negative bacteria such as Acenito baumannii, Klebsiella pneumoniae and Proteus sp. respectively. The results showed that the MIC values of the synthesised compound (Am-h) were 2 μg/mL against Acenito baumannii, Klebsiella pneumoniae, Proteus sp. and Streptococcus sp.
url http://dx.doi.org/10.1155/2010/637549
work_keys_str_mv AT makhloufiamohammed antibacterialactivityofquaternaryammoniumsaltfromdiethylaminoethylmethacrylate
AT benaissatahar antibacterialactivityofquaternaryammoniumsaltfromdiethylaminoethylmethacrylate
AT derdouraicha antibacterialactivityofquaternaryammoniumsaltfromdiethylaminoethylmethacrylate
AT hennidjameleddine antibacterialactivityofquaternaryammoniumsaltfromdiethylaminoethylmethacrylate
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