Diversification of the expanded teleost-specific toll-like receptor family in Atlantic cod, <it>Gadus morhua</it>

Diversification of the expanded teleost-specific toll-like receptor family in Atlantic cod, <it>Gadus morhua</it>

<p>Abstract</p> <p>Background</p> <p>Toll-like receptors (Tlrs) are major molecular pattern recognition receptors of the innate immune system. Atlantic cod (<it>Gadus morhua</it>) is the first vertebrate known to have lost most of the mammalian Tlr orthologu...

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Bibliographic Details
Main Authors: Sundaram Arvind YM, Kiron Viswanath, Dopazo Joaquín, Fernandes Jorge MO
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Evolutionary Biology
Subjects:
Atlantic cod
Toll-like receptors
TLR
Innate immunity
Positive selection
Thermal stress
Neofunctionalisation
Online Access:http://www.biomedcentral.com/1471-2148/12/256

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