Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing.

Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing.

Mammalian RNase H1 has been implicated in mitochondrial DNA replication and RNA processing and is required for embryonic development. We identified the mitochondrial protein P32 that binds specifically to human RNase H1, but not human RNase H2. P32 binds human RNase H1 via the hybrid-binding domain...

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Bibliographic Details
Main Authors: Hongjiang Wu, Hong Sun, Xuehai Liang, Walt F Lima, Stanley T Crooke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3750045?pdf=render

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