Epigenome-Wide Tobacco-Related Methylation Signature Identification and Their Multilevel Regulatory Network Inference for Lung Adenocarcinoma

Tobacco exposure is one of the major risks for the initiation and progress of lung cancer. The exact corresponding mechanisms, however, are mainly unknown. Recently, a growing body of evidence has been collected supporting the involvement of DNA methylation in the regulation of gene expression in ca...

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Bibliographic Details
Main Authors: Yan-Mei Dong, Ming Li, Qi-En He, Yi-Fan Tong, Hong-Zhi Gao, Yi-Zhi Zhang, Ya-Meng Wu, Jun Hu, Ning Zhang, Kai Song
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/2471915